Organo-Post-Transition Metal Compounds
Apexbio Technology LLC Benzoquinonium dibromide 311-09-1 10mg
Benzoquinonium dibromide is a small-molecule antagonist targeting nicotinic acetylcholine receptors (nAChRs) It is designed to inhibit neuronal acetylcholine receptor channel activity thereby regulating cholinergic neurotransmission Benzoquinonium dibromide exerts its biological activity primarily through blockade of nAChRs affecting the permeability of Na and K ions across neuronal membranes In in vitro studies using cultured fetal rat hippocampal neurons Benzoquinonium dibromide demonstrates dual effects at concentrations of 0 1 10 M it activates ion channel currents at conductance states of approximately 43 pS and 30 pS while also exhibiting channel-blocking activity at the open-channel state Based on these pharmacological properties Benzoquinonium dibromide holds research potential in neuropharmacology and neurophysiology for investigating cholinergic signaling pathways receptor activation mechanisms and receptor-channel interactions
eMolecules AstaTech / DIMETHYLTIN DICHLORIDE / 5g / 482917228 / H11302 / 97.000 / 753-73-1 / MFCD00000517 / 219.680 / C2H6Cl2Sn
AstaTech / DIMETHYLTIN DICHLORIDE / 5g / 482917228 / H11302 / 97.000 / 753-73-1 / MFCD00000517 / 219.680 / C2H6Cl2Sn
Sigma Aldrich Fine Chemicals Biosciences Dimethyltin oxide | 2273-45-2 | MFCD00013838 | 25G
Dimethyltin oxide | Mol Wt: 164.78 | 2273-45-2 | MFCD00013838 | 25G
Selleck Chemical LLC W-84 Dibromide-E0382-5MG
W-84 dibromide (HDMPPA) is a potent allosteric modulator of M2-acetylcholine receptors which retards 3HN-methylscopolamine dissociation
Medchemexpress LLC UCL 1684 dibromide | 199934-16-2 | 98.1% | 654.44 g/mol | C34H30Br2N4 | 5 MG
UCL 1684 dibromide is a potent, non-peptidic, nanomolar inhibitor of small conductance calcium-activated potassium (SK) channels, intended for research use in electrophysiology and ion channel studies.
- Potent SK channel blocker with nanomolar activity.
- High purity (98.1%) suitable for biochemical and electrophysiological assays.
- Molecular weight 654.44 g/mol for formulation calculations.
- Solid, white to off-white material for convenient handling and weighing.
- Stable when stored sealed and protected from moisture; follow recommended cold storage for solutions.
Medchemexpress LLC UCL 1684 dibromide | 199934-16-2 | 98.1% | 654.44 | 25 MG
UCL 1684 (dibromide) is a first nanomolar, non-peptidic small conductance calcium-activated potassium (SK) channel blocker. It is effective in preventing the development of atrial fibrillation due to potent atrial-selective inhibition of INa, causing atrial-selective prolongation of ERP secondary to induction of postrepolarization refractoriness. In vitro studies show it produces direct atrial-selective inhibition of sodium channel current (INa) and shifts SS inactivation of cardiac sodium channels. It also induces PRR, decreases Vmax, increases DTE, and extends the shortest S1-S1 interval.
- First nanomolar, non-peptidic SK channel blocker.
- Effective in preventing atrial fibrillation by atrial-selective inhibition of INa.
- Induces atrial-selective prolongation of ERP.
- Increases wenckebach cycle length in vivo.
Medchemexpress LLC Diquat dibromide hydrate | 6385-62-2 | 99.92% | 362.06 | 100 MG
Diquat dibromide hydrate is a comprehensive herbicide. It increases the production of Reactive Oxygen Species (ROS) and triggers mitochondrial autophagy. It generates free radicals like superoxide anions through redox cycles, leading to oxidative stress. Diquat dibromide hydrate is cytotoxic, reproductive, and neurotoxic, and is used in crops such as cotton and soybean to control noxious weeds.
- Appearance: Solid
- Color: Light yellow to yellow
- Formula: C12H14Br2N2O
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture)
- Solubility (In Vitro): 125 mg/mL (345.25 mM) in H2O (requires ultrasonic)
Apexbio Technology LLC Pancuronium dibromide 15500-66-0 10mM (in 1mL DMSO)
Pancuronium dibromide (CAS 15500-66-0) is a small molecule that acts as a competitive antagonist at nicotinic acetylcholine receptors (AChRs) blocking neuromuscular transmission by displacing acetylcholine from its binding sites on the motor end-plate This action results in skeletal muscle relaxation characterized by dose-dependent neuromuscular blockade With an IC50 value of approximately 5 5 nM pancuronium dibromide serves as a potent pharmacological tool for studying cholinergic receptor function neuromuscular signaling pathways and muscle physiology in biomedical research
Medchemexpress LLC UCL 1684 dibromide | 199934-16-2 | 98.07% | 654.44 | 1 MG
UCL 1684 dibromide | 199934-16-2 | 98.07% | 654.44 | 1 MG
Medchemexpress LLC PI3K/Akt/CREB activator 1 | 2708177-73-3 | C19H15F4NO3 | 25 MG
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. It promotes neuronal proliferation, induces differentiation of Neuro-2a cells into a neuron-like morphology, and accelerates the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. This product can be used in research of vascular dementia (VaD).
- Potent, orally active PI3K/Akt/CREB activator.
- Promotes neuronal proliferation.
- Induces differentiation of Neuro-2a cells into a neuron-like morphology.
- Accelerates axon-dendrite polarization of primary hippocampal neurons.
- Enhances neuronal differentiation and axon-dendrite polarization in cultured hippocampal neurons.
- Improves cerebral blood flow recovery and mitigates learning and memory impairment in chronic cerebral hypoperfusion animal models.
eMolecules Diphenyltin dichloride, 96% | 1135-99-5 | MFCD00000516 | 10g
Strem Chemicals | Diphenyltin dichloride, 96% | 10g | 321342865 | 93-5016 | 96.000 | 1135-99-5 | MFCD00000516 | 343.820 | C12H10Cl2Sn
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AdipoGen Diquat dibromide monohydrate
Chemical. CAS 6385-62-2. Formula C12H12Br2N2 . H2O. MW BD9837. Diquat dibromide is a non-selective contact herbicide that produces desiccation and defoliation. When acting as a herbicide, diquat inhibits photosynthesis electron transport. In light-exposed plants, it accepts an electron from photosystem I more specifically ferredoxin, to form its green radical cation. The electron is then transferred to molecular oxygen, producing destructive reactive oxygen species. This compound can be used as a reference compound for analytical studies.
Medchemexpress LLC Diheptylviologen dibromide | 6159-05-3 | MFCD00011997 | 99.2% | 514.38 g/mol | C24H38Br2N2 | 1 ML
DHBP dibromide (Diheptylviologen dibromide) is a research-use compound that inhibits calcium release and exhibits muscle relaxant activity. It is provided as a 10 mM solution in DMSO (1 mL vial) for in vitro experiments and should not be used for human or veterinary applications. The compound is identified by CAS 6159-05-3, molecular formula C24H38Br2N2, and a molecular weight of approximately 514.38 g/mol.
- Inhibits calcium release from intracellular stores.
- Exhibits muscle relaxant activity useful for physiological studies.
- Supplied as a ready-to-use 10 mM solution in DMSO (1 mL).
- High purity (99.17%) suitable for research applications.
- Intended for in vitro research use only.
Medchemexpress LLC Diquat dibromide | 85-00-7 | 99.9% | 1 ML
Diquat dibromide is a quaternary ammonium herbicide supplied as an analytical standard for research applications. This listing corresponds to a 10 mM solution supplied in a 1 mL vial (CAS 85-00-7). Molecular formula C12H12Br2N2; molecular weight 344.05 g/mol.
- Analytical standard suitable for research and analytical use.
- Provided as a 10 mM solution.
- Packaged as a 1 mL vial.
- CAS number 85-00-7 for unequivocal identification.
- Molecular formula C12H12Br2N2 and molecular weight 344.05 g/mol.